CXCR4 and neoplasm: More recently, the GW-749 xenograft tumor was shown to have retained 7 transcribed human genes (CD74, CXCR4, PLAGL2, GFAP, VIM, TP53, EGFR), of which CD74, CXCR4, and PLAGL2, continued to be translated to their respective proteins that were visualized by IHC, as well as hamster X chromosome and human pancentromeric DNA in the same nuclei by FISH [36].