POU2F2 and neuroblastoma: It is particularly noteworthy that published reports show that deregulated expression of either PPARA or POU2F2 can promote oncogenic growth, the developmental function of POU2F2 and HOX genes is to maintain cells in a less-differentiated state [71]–[80], and high expression of ECEL1 gene was reported by Kawamoto et al [81] to associate with favorable prognosis in human neuroblastoma.