Studies of populations of African and Asian descent suggest that the study of IBD genetics in non-European populations may show: 1) same gene, same SNPs, but stronger effects than what has been observed in populations of European descent, for example TNFSF15; [4], [5] 2) same gene, different SNPs than what has been observed in populations of European descent, for example NOD2; [6] as well as 3) different gene, different SNPs contributing to susceptibility. This evidence concerns the gene NOD2 and inflammatory bowel disease.