25% of DA2, 34% of AA3, 7% of OA2 and 63% of OA3 had high levels of p53 in the nucleus, whereas oligodendroglial tumors demonstrated significantly lower levels of nuclear p53 (2.3% in O2, 2.7% in O3) (Supplemental Figure 1A). This evidence concerns the gene TP53 and oligodendroglial tumor.