Correlative analysis between glioma lineage and protein levels showed p53 levels were significantly higher in astrocytic and mixed lineage tumors compared to oligodendroglial tumors while the opposite was true for ATRX; oligodendroglial tumors expressed higher ATRX levels compared to astrocytic and mixed lineage tumors (Figure 2B, C). This evidence concerns the gene ATRX and central nervous system cancer.