Potential mediators of suppression in addition to Foxp3+ Treg are IL-10 producing Foxp3− T cells [50], IL-10 producing regulatory B cells [51], [52], alternatively activated macrophages [53], and tolerogenic dendritic cells [54] that have been shown to mediate suppression during nematode infection in several murine systems. Here, IL10 is linked to Nematoda infectious disease.