IGHE and Increased total eosinophil count: To investigate the possibility of a direct link between IgE and modulation of eosinophil activity in BP, we utilized RT-PCR to detect mRNA of the FcεRI α-, β- and γ-chain [29], [45], [46] in peripheral eosinophils from BP patients (n = 6), healthy controls (n = 3) or patients evaluated for non-BP diseases associated with eosinophilia and/or high IgE (n = 4).