In addition, the regulation of protein stability and degradation by a signaling protein β-catenin in mantle cell lymphoma (MCL) [29] as well as post-transcriptional regulation by ubiquitin-specific-protease 2a (USP2a) and isopeptidase proteins breast cancer cells [52] also up-regulate the expression of FASN. The gene discussed is FASN; the disease is breast cancer.