As for cell surface markers, such as CCR7, CD127, CD11c, and CD103 implicated in M1 macrophages and dendritic cells, both of which have been shown to play proinflammatory role in colitis [20], [23], [25] were not expressed on either subpopulations within CD11b+ cells (Figure 3C). The gene discussed is ITGAX; the disease is colitis.