TEK and infection: Importantly, after 24 hours of infection, lung bacterial loads of Tie2-Myd88−/− +control BM mice were indistinguishable from control+control BM mice, while the difference between Tie2-Myd88−/−+Tie2-Myd88−/− BM mice and control+control BM mice phenocopied the difference between Tie2-Myd88−/− and control mice observed in untransplanted mice (p<0.001, figure 5A).