IGHG3 and malaria: In the context of blood-stage malaria immunity, the interaction of IgG1 and IgG3 with monocytes has been reported to be important for mediating effective antibody-dependent cellular inhibition (ADCI) via monocytes when using antibodies present in the serum of naturally exposed individuals [64]–[66] or those specific for antigens such as MSP3 or GLURP [67]–[69].