TP53 and breast cancer: In p53 wild-type (MCF-7) and p53 mutant-type (MDA-MB-231 and BT-549) breast cancer cells, resveratrol suppressed pAkt and phosphorylation of CCAAT/enhancer binding protein beta (C/EBP-β), which has been identified as a negative regulator of miR-145, leading to upregulation in this miRNA [94].