Publications before January 29, 2014, were searched in the Pubmed using key words including “SGLT1 and cancer,” “SGLT2 and cancer,” “canagliflozin and cancer,” “dapagliflozin and cancer,” “empagliflozin and cancer,” “ipragliflozin and cancer,” “tofogliflozin and cancer,” “luseogliflozin and cancer,” and “BI 44847 and cancer.” Except for the two approved SGLT2 inhibitors (i.e., dapagliflozin and canagliflozin), the incidence of cancer for the other SGLT2 inhibitors was not available. The gene discussed is SLC5A2; the disease is cancer.