Since the most dramatic effect observed following PDGFR knockdown in the RJ348 cells was an inhibition of tumor cell migration [25] , tumor cell migration was evaluated using a scratch wound assay and Regorafenib, Sunitinib and Imatinib were tested at 100 nM, 500 nM and 5 μM. This evidence concerns the gene PDGFRB and neoplasm.