Figure 5B shows that, as expected, latent infection of CD14+ monocytes resulted in an increase in secreted CCL8, similar to our previous observations in latently infected CD34+ cells (16). Treatment of CD14+ monocytes with recombinant LAcmvIL-10 also resulted in a substantial induction of CCL8 expression (Fig. 5B). This evidence concerns the gene CCL8 and disease arising from reactivation of latent virus.