Since germline mutations in BRCA1 and, to a less extent, BRCA2 genes have been found in a variable proportion (ranging from 10% to 30%) of patients with LABC or, mostly, triple-negative breast cancer [28], and such gene dysfunctions seem to be associated with prognosis [29], we also evaluated the prevalence of BRCA1-2 mutations in our series. Here, BRCA1 is linked to triple-negative breast carcinoma.