Reduction in the activity of Cdk2 by antiprogestins is relevant from a therapeutic standpoint because Cdk2 is often upregulated in ovarian cancer cells (Sui et al. 2001) and has been shown to be a valuable targetable molecule in ovarian (Etemadmoghadam et al. 2013) and breast (Achille et al. 2012), as well as other human cancer cells (Molenaar et al. 2009, Long et al. 2010). This evidence concerns the gene CDK2 and ovarian carcinoma.