Such potentiation of cytotoxicity of progesterone by mifepristone was reported also in PR-positive MCF-7 breast cancer cells as well as in PR-negative C4-I cervical carcinoma cells, suggesting that the presence of PR may not be essential for the antigrowth properties of both, progesterone and mifepristone (Fjelldal et al. 2010). The gene discussed is PGR; the disease is breast carcinoma.