Herein, we report that HF diet with a high dietary ω6/ω3 ratio significantly reduced the mRNA expression of Ccr7 and increased the expression of its ligand Ccl19, suggesting that T cells are attracted to the liver and once within it, the microenvironment triggers their differentiation into CCR7- cells and retention in the liver. The gene discussed is CCL19; the disease is hydrops fetalis.