In addition, western blot analysis revealed that the pre-treatment of SB203580 and PDTC abrogated the upregulation of MMP2 and MMP9 induced by IL-17A (Fig. 4C–D, G–H), further demonstrating that IL-17A regulated MMPs expression and invasion of cervical cancer cells via activating p38/NF-κB signal pathway. Here, NFKB1 is linked to cervical carcinoma.