B6 and TLR2 KO mice were challenged with a lethal dose of LVS 35 days after inoculation with LVS clpB. 100% of the B6 and TLR2 KO mice previously inoculated with LVS clpB survived the LVS lethal dose challenge, whereas all naïve mice succumbed to infection (Figure 2A). The gene discussed is CLPB; the disease is infection.