Indeed, by searching the online databases, such as the National Center for Adult Stem Cell Research Parkinson's review database (Sutherland et al., 2009) and ParkDB (Taccioli et al., 2011) that contain manually curated, re-analyzed and annotated microarray datasets from PD patients and PD models, we found several datasets showing the down-regulation of Foxa1 and Foxa2 expression in the SNpc of PD patients (Hauser et al., 2005; Zhang et al., 2005; Moran et al., 2006; Lesnick et al., 2007). This evidence concerns the gene FOXA2 and Parkinson disease.