To underscore the above finding, we genotyped all participants and confirmed the 2D-DIGE data (Fig. OR3) that exclusively two GSTO1*A140 alleles were present in non-APOE ε4 AD patients (n = 20) as compared to 32 % in APOE ε4-positive patients and 38 % in controls (30 % in non-APOE ε4 controls). Here, GSTO1 is linked to Alzheimer disease.