MCF-7 cells (1 × 107 cells per 0.1 mL) with elevated miR-143/145 or ERBB3 levels were implanted subcutaneously into 4-week-old C57/BL6 mice, and tumor growth was then evaluated at day 28 after cell implantation (Figure 4A). The gene discussed is ERBB3; the disease is neoplasm.