As expected, the levels of CD4+ and CD8+cells were clearly low in tumor bearing mice as compared to the normal mice (P<.001, Fig. 6a,b), while an increase was noted in the B cells (P<.003, Fig. 6c), which was maximally decreased after the combined treatment (P<.0006, Fig. 6c). The gene discussed is CD8A; the disease is neoplasm.