Stress related rise in H2S released from cancer cells was associated with increase in cystathionine beta synthase (CBS), one of the enzymes that drives H2S production, concomitant with increase in stress and apoptosis-related Bax and γH2AX, which is a critical factor of the S/G2 DNA-damage checkpoint complex (Figure 1C, D). The gene discussed is BAX; the disease is cancer.