Hypogonadotropic hypogonadism, mental retardation, and demyelinating peripheral neuropathy have been reported in patients with RAB3GAP1 or RAB3GAP2 mutations [34], but the bilateral cataracts, microphthalmia, and microcornea systematically found in patients with the Warburg Micro and Martsolf syndromes were not observed in this family. This evidence concerns the gene RAB3GAP2 and demyelinating polyneuropathy.