PROP1 and female infertility: Mutant mice with anterior pituitary dysfunctions, such as Snell (defect in the pituitary specific transcription factor-1 gene (Pit-1)) and Ames dwarf mice (recessive point mutation in the prophet of Pit1 (Prop-1) or paired-like homeodomain transcription factor in Prop-1), show dwarf characteristics, female infertility and severely low insulin, IGF-1, glucose, and thyroid hormone level.