MSH2 and colorectal cancer: Our findings elucidate that the GA genotypic frequency of hMSH2 was relatively higher in patients than in control (OR 1.81, 95% CI 1.20–2.74, p = 0.004) which is in absolute conformity with data of Poplawski et al., (2006) [21] Significant association of Gly322Asp polymorphism of the hMSH2 gene with breast cancer and colorectal cancer [22] was reported.