XRCC1 and cutaneous melanoma: In a recent report, it was found that the 399Gln allele of XRCC1 was in complete linkage disequilibrium (LD) with the 280His allele of same gene (D′ = 1.0) and the 280His allele was in complete LD with the 194Arg allele in XRCC1 gene (D′ = 1.0) in both whites and African Americans [21] in cutaneous melanoma.