Below the citrate condensation, a new stop in the Krebs cycle favors the citrate efflux from mitochondria, which starts via ATP citrate lyase and acetyl CoA carboxylase the synthesis of fatty acids and lipid membranes for mitotic cells; malonyl CoA closes the entry of fatty acids in mitochondria, rendering tumor cell dependent of ketone bodies and lysolipids sources [3]. The gene discussed is ACLY; the disease is neoplasm.