Some have been highly studied such as TP53 and its degrader HUWE1, and genes involved in protein-tyrosine kinase signals such as EPHA1 and EPHA3. We also identify the less-studied PTK2 and VAV1 genes in the same category, and suggest that they are more important in the study of cancer survivalness than currently appreciated. This evidence concerns the gene EPHA3 and cancer.