In this study, six SNPs in PRM1 (C321A), PRM2 (C248T) and TNP2 (T1019C), (G1272C) and G deletion in nucleotides 1036 and 1046 have been examined in idiopathic infertile men with oligospermia and azoospermia and normal individuals to analyze their relationships with idiopathic male infertility in Iranian cases. This evidence concerns the gene PRM1 and Azoospermia.