No significant association were observed among two SNPs, C321A in the PRM1 (p=0.805), C248T in the PRM2 (p=0), and four SNPs in the TNP2 consisted of C1019T (p=0), G1272C (p=0.654) and G-del 1036 and 1046 (p=0) in 96 infertile males compared to that in 100 normal male controls. This evidence concerns the gene PRM2 and Infertility.