ADAM17 and acute myeloid leukemia: The other AML cell lines HL-60 (myeloblastic/M2), NB4 (promyelocytic/M3) and THP-1 (monoblastic/M5) coexpressed surface CD13 and ADAM17, whose levels fell on MY7-treated cells but did not change on untreated or IgG1-treated cells (Figure 5C).