VEGF/VEGFR-2 ratio was more accurate to differentiate malignant potential of ovarian tumors than measurements of VEGF or sVEGFR-2 alone and might reflect the situation that more VEGF is available to bind full-length VEGFR-2 due to the lesser amount of soluble VEGFR-2. The gene discussed is VEGFA; the disease is ovarian neoplasm.