UBQLN2 and colorectal carcinoma: Consistent with our microarray results where we observed down-regulation of UBQLN2 mRNA in both KRAS-WT and KRAS-Mutant, we found that over-expression of miR-126 down-regulated UBQLN2 mRNA in the CRC cell line panel, irrespective of KRAS mutation status (Figure S7B).