Next, we transfected 6 additional CRC lines that included 2 that were KRAS-WT (RKO and CaCo2) and 4 that harbor mutations in KRAS (LoVo, SW403, SW1116 and SW620) to determine whether the KRAS mutant-specific effects of these 15 miRNAs extended to other CRC lines. This evidence concerns the gene KRAS and colorectal carcinoma.