To determine that the dependency of KRAS-Mutant cells for UBQLN2 was not restricted to HCT116 cells, we transfected the KRAS-Mutant CRC lines LoVo and SW620 with siCTL, UBQLN2 siRNA, or miR-126 mimics for 48 h and performed soft agar colony formation assays, assessing colony formation after 3 weeks. This evidence concerns the gene UBQLN2 and colorectal carcinoma.