NDE1 and neoplasm: We did not find tumors in Nde1+/−Trp53+/− mice (n > 30), but approximately one third of the Nde1−/−Trp53+/− mice (∼10 out of >30) developed tumors predominantly of hematopoietic lineages including lymphoma and tumor of the thymus (Figure 6—figure supplement 1A).