However, we confirmed that the CRL-4003 cells were useful in identifying both the hormonal status (estrogen receptor (ER) and progesterone receptor (PR)) and expression of DCN mRNA treated with dienogest in primary cultured endometriotic stromal cells (HMOsis scl2 and HMOsis scl3) and the CRL-7566 endometriosis cell line (Supplementary Figure 1, see section on supplementary data given at the end of this article). The gene discussed is ESR1; the disease is endometriosis.