Interactions of some of these variants such as Hb Q-Thailand, Hb Hope, Hb Tak, Hb Korle-bu, Hb Beijing, Hb Hekinan, Hb J-Bangkok, Hb Pyrgos, Hb Siam, Hb Queens, Hb C, Hb D-Punjab, Hb Nakhon Ratchasima and Hb Phimai with thalassemia and hemoglobinopathies have been reported [12]–[30]. The gene discussed is GSTM1; the disease is hemoglobinopathy.