In particular, although initial systematic reviews of published literature on the topic put forward a promising effect on management of anemia and failed to demonstrate a significant efficacy in controlling dyslipidemia [83], a recent meta-analysis involving more than 1700 participants failed to confirm the previous findings regarding the effects of L-carnitine on hemoglobin but showed that L-carnitine significantly decreases serum low-density lipoprotein (LDL) and C-reactive protein (CRP). This evidence concerns the gene CRP and anemia.