TMPRSS2 and posterior cortical atrophy: Many excellent reviews have summarized novel candidate biomarkers including proteins (e.g., α-methylacyl-CoA racemase, endoglin, prostate-specific membrane antigen [PSMA], caveolin-1, interleukin-6, CD147, TGF-β 1, and human kallikrein-2), genetic biomarkers (e.g., TMPRSS2:ETS gene fusions, BRCA1/2 mutations), epigenetic modification (e.g., methylation of the glutathione S-transferase [GSTP1] gene and histone modifications), and expression of (novel) mRNA transcripts in PCa [6, 15–19].