IL4 and allergic disease: In our model, while the expression of IL-4 that plays a central role in inflammatory response in allergy was significantly higher in the BALF of OVA-challenged Scgb3a2−/−(N6) mice compared to that from OVA-challenged Scgb3a2+/+(N6) mice, the inflammatory indexes determined based on the histological features of lungs and inflammatory cell numbers in BAL were not significantly different between the OVA-challenged Scgb3a2−/−(N6) and Scgb3a2+/+(N6) mice.