Although our secondary meta-analysis of CB COPD relative to COPD without CB within the COPD population failed to demonstrate genome-wide significant SNPs, the fourth most significant SNP, rs2298019, was previously identified as an expression quantitative trait locus (eQTL) for ATF6 in lung tissue [51], with the risk allele associated with decreased expression. The gene discussed is ATF6; the disease is chronic obstructive pulmonary disease.