On univariable analysis, young age (36–50 vs. ≤35, P = 0.042), tumor size (T2 vs. T1, P = 0.014), positive nodes (LN+ vs. LN−, P = 0.032) and HER-2 subtype (HER-2 vs. luminal A, P = 0.016) were independently associated with increased risk of LR (Table 5). Here, ERBB2 is linked to neoplasm.