A multivariate Cox model revealed independent prognostic roles for tumor size (T2 vs. T1, P = 0.001), node status (LN+ vs. LN−, P = 0.044), and HER-2 subtype (HER-2 vs. luminal A, P = 0.031) in LR (Table 6). The gene discussed is ERBB2; the disease is neoplasm.