APOE and frontotemporal dementia: In our disease subgroups (Table 2; Figure 2), we observed significant associations in our FTD probands for rs7403881 (MT-Ie; RR = 3.81; p-value = 0.001; recessive genotypic model), rs13268953 (ELP3; RR = 3.65; p-value = 0.003; recessive genotypic model), and the epsilon 4 allele (apolipoprotein E [APOE]; rs429358 and rs7412; RR = 3.13; p-value = 0.004; dominant genotypic model).