Several reports have also shown that 1,25D3 regulates antimüllerian hormone (AMH) signalling, follicle-stimulating hormone sensitivity, and progesterone production in human granulosa cells, and decreases the abnormally elevated AMH levels in 1,25D3-deficient women with PCOS, indicating a critical role for 1,25D3 in follicular development [50]. The gene discussed is AMH; the disease is polycystic ovary syndrome.