Sucrose density gradients showed that an amount of AhR protein was found in Cav-1-containing DRM fractions of T-FGM AhR+/+ fibroblasts (Figure 3B, upper) and, importantly, of phenotypically unrelated mouse Hepa1 hepatoma cells (Figure 3B, lower). The gene discussed is CAV1; the disease is hepatocellular carcinoma.