CERS2 and chronic kidney disease: In a pre-specified investigation of 16 SNPs that were previously found to be associated with eGFR we found that one SNP (rs267734) in the CERS2 gene was associated with annual rate of increase in albuminuria in patients with diabetes from ONTARGET and TRANSCEND after adjusting for other established risk factors for CKD progression including baseline albuminuria and baseline eGFR.