Following ileitis induction (day 0) T. gondii infected mice were treated with synthetic PACAP (1.5 mg per kg body weight per day) via the intraperitoneal route, either from day 1 until day 6 (prophylactic regimen) post infection (p.i.)or starting on day 4, when first histopathological ileum mucosal changes can be observed [21], until day 6 following ileitis induction (therapeutic treatment) and compared to control animals. This evidence concerns the gene ADCYAP1 and Crohn ileitis.