Lastly, as GBM is comprised of 5 molecular subtypes (Proneural, Neural, Classical, Mesenchymal, and the G-CIMP positive subgroup), we compared LIMK1 and LIMK2 among the varying subgroups of GBM from the TCGA dataset and observed no subtype differences (Figures 2E-F). The gene discussed is LIMK2; the disease is glioblastoma.