FASN and breast carcinoma: The fatty acid metabolism pathway is found to be crucial to maintain the cancer cell malignant phenotype, and higher expression of fatty acid synthase has been discovered as a common phenotype in breast cancer with a poorer prognosis [41]; As another example, Src kinase activation by protein tyrosine phosphatase alpha (SRCRPTP_PATHWAY), has been discovered in invasive breast cancer with compelling evidences.