This may have been due to greater level of bacteremia experienced by the IL-1β deficient mice (WT n = 13, 2.47×108±4.36×107 CFU/mL blood; Caspase-1 KO n = 6, 7.82×108±3.18×108 CFU/mL blood; P = 0.012). This evidence concerns the gene IL1B and bacterial infectious disease with sepsis.