Additionally, apart from the glycogenes which have been reported previously like mgat1, mgat5 and st3gal1, some glycogenes such as “UDP-N-acetyl-α-D-galactosamine: polypeptide N-acetylgalactosaminyltransferase” family members: galnt3, galnt4, galnt11, galnt13, and “mannosidase, α class” family members, for instance, man1b1, man1c1, man2a2, their different expressions were associated with HCC metastasis are the first reported. Here, MAN2A2 is linked to hepatocellular carcinoma.