Similar number of live viral particles were found in the lungs of all three strains of mice 2 days after infection with influenza A virus, however, the number of viral particles was significantly reduced in SP-C-Cre+/+/LepRfl/fl, and LysM-Cre+/+/LepRfl/fl mice compared to control mice on day 4 after infection (Figure 4). Here, SFTPC is linked to infection.